Heritability of recombination frequency
نویسندگان
چکیده
منابع مشابه
On the frequency of undetectable recombination events.
Simple analytical results show that many recombination events occur in such a way as to have no effect on the resultant DNA sequence. The proportion of these undetectable events depends on the population size, mutation rate and recombination rate and is quite large for reasonable values of these quantities. Efforts to estimate recombination rates and frequencies directly from DNA sequence data ...
متن کاملText S2: References for disease frequency and heritability
Citations to papers providing lifetime morbid risks and heritabilities, and proportions of heritability explained are provided in Tables S6 and S7. Where multiple values for heritability are shown in Table S7, we used an inverse variance weighted average to obtain the value shown in Table 2. For age-related macular degeneration (AMD), celiac disease, Crohn disease, and ulcerative colitis, the v...
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At the restrictive conditions (35 degrees under continuous light) Coprinus lagopus is unable to initiate premeiotic S phase which takes place normally within 8-10 h of karyogamy. A shift-up to the restrictive conditions causes an arrest of the basidiocarps at this critical stage. A prolonged arrest causes a reversal to mitosis (Lu 1974b). Incubation of basidiocarps at the restrictive conditions...
متن کاملDependence of frequency of homologous recombination on the homology length.
The frequency of homologous recombination is believed to be a linear function of the length (N bp) of homology between DNAs. Here, the N intercept is believed to be determined by a threshold length below which some physical constraint is effective. In the mammalian gene targeting systems, however, the frequency depends more steeply than linearly on the homology length. To explain both the linea...
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Mammalian expression systems, due to their capacity in post-translational modification, are preferred systems for biopharmaceutical protein production. Several recombinant protein systems have been introduced to the market, most of which are under clinical development. In spite of significant improvements such as cell line engineering, introducing novel expression methods, gene silencing and pr...
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ژورنال
عنوان ژورنال: Hereditas
سال: 2009
ISSN: 0018-0661
DOI: 10.1111/j.1601-5223.1973.tb01136.x